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Company History
2009
2011
2014
2015
2016
2018
2019
2020
2021
2022
2023
2009
Our Company was established in Beijing, China as our headquarters to commence research and development of biotechnology in the China
2011
Developed ESC/HR-based gene editing technology platform and delivered our gene editing services to our first customer
2014
Developed CRISPR/EGE-based gene editing technology, which enables simultaneous gene knock-in of two genes in rats Developed the severe immunodeficient B-NDG™ mice and developed a series of immune checkpoint humanized mice based on the genetic background of C57BL/6
2015
Established a comprehensive pharmacology service platform, covering cell-based functional assays, pharmacokinetic assays and drug metabolism assays Completed the series B round financing and raised an aggregate amount of approximately RMB40 million
2016
Haimen animal center began operations and obtained AAALAC credentials; Established antibody discovery platform; Established Eucure to engage in clinical and preclinical development of drug candidates。
2018
Biocytogen Boston Corp began operation
2019
Developed technology for megabase-scale chromosomal editing and released RenMab Mice, a fully human antibody mouse model Obtained approval for commencing Phase I clinical trials of YH001 in patients with advanced solid tumors in the U.S.
2020
Completed first patient screening for Phase I clinical studies of YH001, YH002 and YH003 in Australia Launched Project Integrum, a large-scale in vivo antibody discovery program
2021
Completed first patient screening for Phase I clinical study of YH001 and obtained approval to initiate Phase I clinical trial of YH003 in the PRC Completed Phase I clinical trial of YH003, entered Phase II clinical study of YH003 in Australia, and obtained approvals to commence Phase II clinical trials for YH001 and YH003 in the U.S. and Phase I clinical trial of YH004 in Australia.
In September
Listed on the Main Board of the Stock Exchange of Hong Kong
In March
Established Biocytogen Europe Innovation Center in Heidelberg
In May
Opened San Francisco office