Strain Name
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C57BL/6-Nkg2dtm2(NKG2D)Bcgen/Bcgen
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Common Name
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B-hNKG2D mice plus
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Background
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C57BL/6
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Catalog number
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112497
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Aliases
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NKG2D (KLR; CD314; KLRK1; NKG2-D; D12S2489E)
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Protein expression analysis in CD4+T cells
Strain specific analysis of NKG2D expression in wild-type (WT) mice (+/+) and homozygous B-hNKG2D mice plus(H/H) by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hNKG2D mice plus (H/H), and analyzed by flow cytometry with species-specific anti-NKG2D antibody. mNKG2D and hNKG2D were not detectable in CD4+T cells of wild-type and homozygous B-hNKG2D mice plus.
Protein expression analysis in CD8+T cells
Strain specific analysis of NKG2D expression in wild-type (WT) mice (+/+) and homozygous B-hNKG2D mice plus(H/H) by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hNKG2D mice plus(H/H), and analyzed by flow cytometry with species-specific anti-NKG2D antibody. mNKG2D was not detectable in CD8+T cells of wild-type C57BL/6 mice, while hNKG2D was detectable in homozygous B-hNKG2D mice plus.
Protein expression analysis in NK cells
Strain specific analysis of NKG2D expression in wild-type (WT) mice (+/+) and homozygous B-hNKG2D mice plus(H/H) by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hNKG2D mice plus(H/H), and analyzed by flow cytometry with species-specific anti-NKG2D antibody. mNKG2D was detectable in NK cells of wild-type C57BL/6 mice and homozygous B-hNKG2D mice plus, while hNKG2D was only detectable in homozygous B-hNKG2D mice plus.