||B-Tg(Luc) HCT 116||Catalog number||321974|
B-Tg(Luc) HCT 116 cells (1x105, 5x105 ,1x106) were injected into the colon of wild-type B-NDG mice. Signal intensity and body weight were measured twice a week. (A) Imaging was performed twice a week. (B) Body weight (Mean ± SEM). B-Tg(Luc) HCT 116 cells can be used for in vivo efficacy evaluation.
Histopathological HE staining was performed in two suspected tumor metastasis tissue samples.
Tumor growth curve & Body weight changes
Subcutaneous homograft tumor growth of B-Tg(Luc) HCT 116 cells. B-Tg(Luc) HCT 116 cells (5x106) were subcutaneously implanted into B-NDG mice (female, 8-week-old, n=5). Tumor volume and body weight were measured twice a week. (A) Average tumor volume ± SEM. (B) Body weight (Mean± SEM). Volume was expressed in mm3 using the formula: V=0.5 X long diameter X short diameter2. As shown in panel A, B-Tg(Luc) HCT 116 cells were able to establish tumors in vivo and can be used for efficacy studies.