Form submission_Biocytogen Pharmaceuticals (Beijing) Co., Ltd._Biocytogen, drug development, antibody discovery

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AACR 2022: Generation of TCR-mimic fully human antibodies against HLA-antigen-peptide complexes using HLA transgenic RenMice

We describe an HLA transgenic mouse that acquires fully human TCR mimic antibodies through a proprietary immunization procedure. Beacon on-chips screening and high-throughput binding validation accelerate antibody discovery. Diversified antibody sequences ensure the screening of antibodies with high specificity and high affinity.

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