Conduct in vivo pharmacokinetic studies (including absorption, distribution, metabolism and excretion) to support drug screening and clinical translation studies.
1. Methodology establishment and validation
2. Plasma concentration study
3. Immunogenicity, anti-drug antibody (ADA) study
4. Biodistribution study
5. Receptor occupancy study
6. PK/PD modeling
ELISA, MSD, FACS, animal fluorescence imaging