Establishment of SLE Mouse Model based on Balb/c Mice

Content of Proteinuria in urine (A) and mouse Anti-dsDNA IgG in serum (B) were elevated after treatment with Pristane.

Histologic Assessment of SLE in Balb/c Mice

Histological analysis of the kidneys of SLE model. H&E staining(A), PAS staining(B) and Masson staining(C) showed that glomerular stromal cell hyperplasia, glomerulosclerosis, protein tubular pattern and fibrosis in the model group.