Cre Mouse/Rat Models_Biocytogen Pharmaceuticals (Beijing) Co., Ltd._Biocytogen, drug development, antibody discovery

Product No	Product	Application area
110880	B-Epor-EGFP-iCre mice	Function research of genes/erythrocytes
110140	B-Cdh5-iCreERT2 mice	Function research of genes； Research on cardiovascular system, tumor and cell differentiation mechanism
110147	B-CAG-iCreERT2 mice	Function research of genes； Systemic knockout of lethal target genes in embryos
210501	B-Oxt-iCre rats	Function research of genes. This OxtiCre model is an efficient tool to study various gene functions when crossed with rats with different loxP site-flanked genes of interest, especially in studies of Oxytocin expressed in the PVN, SON and the olfactory cue. The development of social familiarity in rodents depends predominantly on olfactory cues and can critically influence reproductive success.
210488	B-Drd2-Cre rats	Function research of genes. This Drd2Cre model is an efficient tool to study various gene functions when crossed with rats with different loxP site-flanked genes of interest, especially in studies of D2 dopamine receptor subtype-expressing neurons, and may be useful for studying dopamine-sensitive behaviors such as addiction.
110780	B-Camk2a-iCre-EGFP mice	Function research of genes. Function research of synaptic plasticity and Long Term Potentiation (LTP) in hippocampal networks
110779	B-Cx3cr1-iCreERT2-EGFP mice	Function research of genes .Function research of microglial cells and other Cx3cr1-expressing immune cells
110155	B-Pgr-iCre mice	Function research of genes. Function research of reproductive system
110146	B-Tagln-iCre mice	Function research of genes . Function research of smooth muscle cell
110144	B-Gfap-iCre mice	This Gfap-iCre model is an efficient tool to study various gene functions when crossed with mice with different loxP site-flanked genes of interest, especially in studies of astrocytes cells related signaling.
110141	B-Tcf21-iCreERT2 mice	Function research of genes. This Tcf21iCreERT2 model is an efficient tool to study various gene functions when crossed with mice with different loxP site-flanked genes of interest, especially in studies of Transcription factor 21 expressed during mouse embryogenesis specifically in mesodermally-derived cells that surround the epithelium of the developing gastrointestinal, genitourinary, and respiratory systems, and may be useful for studying mouse embryonic development.
110139	B-Htr2c-iCre mice	Function research of genes. This Htr2ciCre model is an efficient tool to study the various gene functions when crossed with mice with different loxP site-flanked genes of interest.
110134	B-Ucp1-iCre mice	Function research of genes. This Ucp1iCre model is an efficient tool to study various gene functions when crossed with mice with different loxP site-flanked genes of interest, especially in studies of the balance of ATP synthesis and thermogenesis in the mitochondria of brown adipose.
110131	B-Sp7-iCre mice	Function research of genes. This Sp7iCre model is an efficient tool to study various gene functions when crossed with mice with different loxP site-flanked genes of interest, especially in studies of bone development, osteoblast lineage, and Hedgehog/Wnt signaling.
110130	B-Prrx1-iCre mice	Function research of genes. This Prrx1iCre model is an efficient tool to study various gene functions when crossed with mice with different loxP site-flanked genes of interest, especially in studies of mesodermal development, such as cardiac, skeletal development and signaling.
110129	B-Pdgfrb-iCre mice	Function research of genes .This PdgfrbiCre model is an efficient tool to study the various gene functions when crossed with mice with different loxP site-flanked genes of interest.
110127	B-Nkp46-iCre mice	Function research of genes. This Ncr1iCre model is an efficient tool to study various gene functions when crossed with mice with different loxP site-flanked genes of interest, especially in studies of natural killer (NK) cells related signaling.
110125	B-Grpr-iCre mice	Function research of genes .This GrpriCre model is an efficient tool to study various gene functions when crossed with mice with different loxP site-flanked genes of interest, especially in studies of pruritogenic stimuli, long-term potentiation (LTP) and amygdala-dependent memory for fear.

Biocytogen is headquartered in Beijing, with branches in Haimen, Jiangsu, Boston, Shanghai. Its wholly-owned subsidiary, Eucure Biopharma, focuses on clinical development.